| 8/24/24 | Hoffenheim 3:2 Holstein Kiel | 0.00 | 0.00 | 3 | 3.00 | Home vs 17 |
| 8/31/24 | Ein Frankfurt 3:1 Hoffenheim | −1.80 | −1.80 | 0 | 1.80 | Away to 4 |
| 9/14/24 | Hoffenheim 1:4 Leverkusen | −3.50 | −1.70 | 0 | 1.70 | Home vs 3 |
| 9/21/24 | Union Berlin 2:1 Hoffenheim | −6.10 | −2.60 | 0 | 2.60 | Away to 14 |
| 9/29/24 | Hoffenheim 3:4 Werder Bremen | −8.70 | −2.60 | 0 | 2.60 | Home vs 9 |
| 10/6/24 | Stuttgart 1:1 Hoffenheim | −10.10 | −1.40 | 1 | 2.40 | Away to 10 |
| 10/19/24 | Hoffenheim 3:1 Bochum | −10.10 | 0.00 | 3 | 3.00 | Home vs 18 |
| 10/27/24 | Heidenheim 0:0 Hoffenheim | −11.80 | −1.70 | 1 | 2.70 | Away to 16 |
| 11/2/24 | Hoffenheim 0:2 St Pauli | −14.60 | −2.80 | 0 | 2.80 | Home vs 15 |
| 11/10/24 | Augsburg 0:0 Hoffenheim | −16.10 | −1.50 | 1 | 2.50 | Away to 13 |
| 11/23/24 | Hoffenheim 4:3 RB Leipzig | −15.60 | +0.50 | 3 | 2.50 | Home vs 8 |
| 12/1/24 | Mainz 2:0 Hoffenheim | −17.70 | −2.10 | 0 | 2.10 | Away to 7 |
| 12/8/24 | Hoffenheim 1:1 Freiburg | −18.90 | −1.20 | 1 | 2.20 | Home vs 6 |
| 12/15/24 | Dortmund 1:1 Hoffenheim | −19.80 | −0.90 | 1 | 1.90 | Away to 5 |
| 12/21/24 | Hoffenheim 1:2 M'gladbach | −22.40 | −2.60 | 0 | 2.60 | Home vs 11 |
| 1/11/25 | Hoffenheim 0:1 Wolfsburg | −25.20 | −2.80 | 0 | 2.80 | Home vs 12 |
| 1/15/25 | Bayern Munich 5:0 Hoffenheim | −26.40 | −1.20 | 0 | 1.20 | Away to 2 |
| 1/18/25 | Holstein Kiel 1:3 Hoffenheim | −26.20 | +0.20 | 3 | 2.80 | Away to 17 |
| 1/26/25 | Hoffenheim 2:2 Ein Frankfurt | −27.20 | −1.00 | 1 | 2.00 | Home vs 4 |
| 2/2/25 | Leverkusen 3:1 Hoffenheim | −28.50 | −1.30 | 0 | 1.30 | Away to 3 |
| 2/8/25 | Hoffenheim 0:4 Union Berlin | −31.30 | −2.80 | 0 | 2.80 | Home vs 14 |
| 2/16/25 | Werder Bremen 1:3 Hoffenheim | −30.60 | +0.70 | 3 | 2.30 | Away to 9 |
| 2/23/25 | Hoffenheim 1:1 Stuttgart | −32.20 | −1.60 | 1 | 2.60 | Home vs 10 |
| 3/1/25 | Bochum 0:1 Hoffenheim | −32.00 | +0.20 | 3 | 2.80 | Away to 18 |
| 3/9/25 | Hoffenheim 1:1 Heidenheim | −34.00 | −2.00 | 1 | 3.00 | Home vs 16 |
| 3/14/25 | St Pauli 1:0 Hoffenheim | −36.70 | −2.70 | 0 | 2.70 | Away to 15 |
| 3/29/25 | Hoffenheim 1:1 Augsburg | −38.50 | −1.80 | 1 | 2.80 | Home vs 13 |
| 4/5/25 | RB Leipzig 3:1 Hoffenheim | −40.70 | −2.20 | 0 | 2.20 | Away to 8 |
| 4/12/25 | Hoffenheim 2:0 Mainz | −40.00 | +0.70 | 3 | 2.30 | Home vs 7 |
| 4/19/25 | Freiburg 3:2 Hoffenheim | −42.00 | −2.00 | 0 | 2.00 | Away to 6 |
| 4/26/25 | Hoffenheim 2:3 Dortmund | −44.20 | −2.20 | 0 | 2.20 | Home vs 5 |
| 5/3/25 | M'gladbach 4:4 Hoffenheim | −45.70 | −1.50 | 1 | 2.50 | Away to 11 |
| 5/9/25 | Wolfsburg 2:2 Hoffenheim | −47.20 | −1.50 | 1 | 2.50 | Away to 12 |
| 5/17/25 | Hoffenheim 0:4 Bayern Munich | −48.90 | −1.70 | 0 | 1.70 | Home vs 2 |